All eyes are as soon as once more on Cristiano Ronaldo as Manchester United goals make amends for a shock Champions League defeat to Young Boys when the Premier League chief heads to West Ham on Sunday.
Second-placed Chelsea is behind United solely on objectives scored and can look to increase its unbeaten begin in a London derby at Tottenham.
Liverpool and Manchester City won’t count on to be anxious when Crystal Palace and Southampton go to Anfield and the Etihad respectively on Saturday.
Pressure on Arteta
But the stress is on under-fire Arsenal boss Mikel Arteta when the Gunners journey to fellow struggler Burnley.
Ole Gunnar Solskjaer has demanded a direct response from United after the optimism engendered by Ronaldo’s return was punctured in Bern.
Chelsea striker Romelu Lukaku will go face to face with Tottenham’s Harry Kane in a captivating shoot-out between two of the Premier League’s main marksmen.
Lukaku has already scored 4 instances in 4 appearances, together with a perfectly-timed header to interrupt Zenit Saint Petersburg’s cussed resistance within the Champions League in midweek.
Saturday: Wolves v Brentford, Aston Villa v Everton, Burnley v Arsenal, Liverpool v Crystal Palace, Manchester City v Southampton, Norwich v Watford.
Sunday: Brighton v Leicester, West Ham v Manchester United, Tottenham v Chelsea.